Uterine fibroids or Leiomyomas are benign tumors of uterus. Genetic abnormalities, alteration in growth factor (proteins formed in the body that direct the rate and extent of cell proliferation) expression, abnormalities in the vascular (blood vessel) system, and tissue response to injury have all been suggested to play a role in the development of uterine fibroids. Every year thousands of women hear the frightening diagnosis of fibroids in the uterus. In most of the women, uterine fibroids are caused when exposed to high levels of toxins, these toxins are artificial chemicals that are structurally similar to the Estrogen, naturally found in the human body. The present review focuses on the pathology, diagnosis, histology, medication options and surgical treatment of fibroids.
Key words: Estrogen, fibroids, tumors