Background: Low density lipoprotein cholesterol (LDL-C), for many years has been a good and established marker for coronary artery disease (CAD). But many people with normal LDL-C are found to be suffering from CAD. This indicates that along with LDL-C, triglycerides and other cholesterols except HDL-C should be considered while predicting CAD. Thus, nowadays non HDL-C is gaining more importance as predictor of CAD. This study aims at establishing the role of non HDL-C in predicting CAD. Methods: This is a prospective cross sectional study and comprised a total of 100 subjects which includes equal number of study group and control. Study group includes patients diagnosed with CAD based on ECG, ECHO report and other biomarkers. Control group consisted of subjects without CAD who attended master health check-up in RMMCH with no history of CAD. Their lipid profile parameters were analyzed using ERBA CHEM 5+V2 (Semi Auto Analyzer) and statistical analysis was done. Results: Out of 50 CAD patients in study group, 28 were male and 22 were female and majority of CAD diagnosed patients were in the age group of 56-75 years. There were statistically significant differences in LDL-C (p=0.039) and non-HDL-C (p=0.027) levels when study and control groups were compared. Conclusion: Our study concludes that non HDL-C having a better predictive value than LDL-C for atherosclerosis, especially in patients with TGL levels > 150 mg/dl.
Key words: Coronary Artery Disease (CAD), High density lipoprotein, Low density lipoprotein, Triglycerides, Cholesterol.