Incidence and Factors Associated with Drug Related Hospital Admissions in a South Indian Tertiary Care Hospital

Published on:March 2018
Indian Journal of Pharmacy Practice, 2018; 11(1):37-43
Original Article | doi:10.5530/ijopp.11.1.7


Incidence and Factors Associated with Drug Related Hospital Admissions in a South Indian Tertiary Care Hospital


Authors and affiliation (s):

Sravya Gethika Dammalapati1, Siva Reddy Challa2*, Prasad Challa1, Mohammed Irfan1, Kavitha Chanumolu1, Ravindra Babu Pingili2, Krishna Sri Nalla2, Eswar G3

1Department of Pharmacy Practice, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, INDIA.

2Department of Pharmacology, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, INDIA.

3Department of General Medicine, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation Chinoutpalli, Gannavaram, Krishna, Andhra Pradesh, INDIA.

Abstract:

Objective: The study aimed to assess the incidence, nature of drug related hospital admissions (DRHAs) and factors associated with DRHAs. Method: A retrospective study was conducted to evaluate the medical records of patients admitted to general medicine department for six months. Drug related hospital admissions were assessed using Helper and Stand Classification. Crude odds ratio (COR) and adjusted odds ratio (AOR) were determined using univariate and multivariate logistic regression analysis. Results: The results of analysis of 1177 medical records reveal that 202 (17.2%) patients were admitted due to 248 DRHAs. Of which, the most common DRHA was non-compliance that accounted for 50.50% (102). Out of 248 drug related hospital admissions, 65.8% (n=163) were definitely preventable, 30.2% (n=75) were possibly preventable and 4.0% (n=10) were definitely not preventable. However, multivariate regression analysis results indicate that hypertension, diabetes mellitus, and polypharmacy at admission are significantly (p< 0.001) associated with DRHA. Conclusion: The factors remarkably associated with drug related hospital admissions are age, diabetes mellitus, hypertension and polypharmacy. The major reasons for drug related hospital admissions are non-compliance and adverse drug reactions. Collaborative efforts among patients, physicians, pharmacists and caregivers might reduce the frequency of drug related hospital admissions.

Key words: Drug related hospital admissions, Adverse drug reactions, Compliance, Retrospective study, Risk factors.




 

The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
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