Comparing the Safety between Ferrous Carboxymaltose and Iron Sucrose Therapy in Iron Deficiency Anemia during Pregnancy in Obstetrics and Gynecology Ward at Tertiary Care Hospital, Jaipur

Published on:August 2019
Indian Journal of Pharmacy Practice, 2019; 12(3):167-170
Original Article | doi:10.5530/ijopp.12.3.37


Comparing the Safety between Ferrous Carboxymaltose and Iron Sucrose Therapy in Iron Deficiency Anemia during Pregnancy in Obstetrics and Gynecology Ward at Tertiary Care Hospital, Jaipur


Authors and affiliation (s):

Kamal Saini1,*, Rajveer Singh1, Divyani Agrawal2

1Department of Pharmacy Practice, NIMS Institute of Pharmacy, NIMS University, Jaipur, Rajasthan, INDIA.

2Department of Obstetrics and Gynecology, NIMS University, Jaipur, Rajasthan, INDIA.

Abstract:

Background: Pregnancy is the most vulnerable condition prone for anemia (most commonly iron deficiency anemia). Hence requires drug therapy for iron store replenishment. Comparing the safety between ferrous carboxymaltose and iron sucrose therapy in iron deficiency anemia during pregnancy in obstetrics and gynecology ward at a tertiary care hospital. Methods: A prospective observational single centered study was conducted on 60 pregnant women who were diagnosed with iron deficiency anemia in the department of obstetrics and gynecology at tertiary care teaching hospital. The subjects were divided into two groups, first group was administered iron sucrose 200mg and second group was administered ferrous carboxymaltose 500mg. The relative incidence of drug administrative adverse event was low in Ferrous Carboxymaltose than compare to Iron Sucrose. Result: The adverse event occurred in 3.33% for Ferrous Carboxymaltose and 13.33% for Iron Sucrose. The mean rise of hemoglobin was 2.92 g/l for Ferrous Carboxymaltose and 1.08 g/l for iron sucrose. Conclusion: In this study it was found that Ferrous carboxymaltose is safer in comparison to the Iron sucrose among the pregnant women with Iron deficiency anemia.

Key words: Ferrous Carboxymaltose, Iron Sucrose, Iron Deficiency Anemia, Pregnant woman, Haemoglobin.




 

The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
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