Prescription Pattern and Drug Utilization Analysis in Patients with Acute Coronary Syndrome

Published on:December 2019
Indian Journal of Pharmacy Practice, 2020; 13(1):73-79
Research Article | doi:10.5530/ijopp.13.1.12


Prescription Pattern and Drug Utilization Analysis in Patients with Acute Coronary Syndrome


Authors and affiliation (s):

Dona Saju1,*, Cristina Joy1, Moushmi Arul Moorthy1, Bivin Wilson2, Jithin Antony3, Sengottuvelu Singaravel4, Sheik Haja Sherief4, Sivakumar Thangavel5

1Department of Pharmacy Practice, Nandha College of Pharmacy, Perundurai Main Road, Erode, Tamil Nadu, INDIA.

2Consultant Interventional Cardiologist, G. Kuppuswamy Naidu Memorial Hospital, Papanaickenpalayam, Coimbatore, Tamil Nadu, INDIA.

3Department of Clinical Pharmacy, G. Kuppuswamy Naidu Memorial Hospital, Papanaickenpalayam, Coimbatore, Tamil Nadu, INDIA.

4Department of Pharmacology, Nandha College of Pharmacy, Perundurai Main Road, Erode, Tamil Nadu, INDIA.

5Department of Pharmaceutical Chemistry, Nandha College of Pharmacy, Perundurai Main Road, Erode, Tamil Nadu, INDIA.

Abstract:

Background: Acute Coronary Syndrome (ACS) is one of the major causes of morbidity and mortality in developing countries, which illustrates the need for rational prescribing of drugs to the patients. Aim: The aim of the study is to analyse the prescription pattern and drug utilisation for the drugs prescribed to the patients with ACS by checking the compliance with the standard guidelines provided by the American College of Cardiology/American Heart Association (ACC/AHA). Materials and Methods: A prospective observational study for a period of 6 months was conducted in the cardiology and cardiothoracic departments of a tertiary care hospital. The sample size was determined by using Rao software and percentage of the data was calculated using Microsoft Excel 2007. Results: A total of 270 patients were enrolled in the study in which males (219) dominated females (51) and were found in the age group of 60-69 years (92). Diabetes (62.9%) followed by hypertension (54.8%) were found to be the dominant risk factors. The prescribing frequency of dual antiplatelet therapy, statins, beta blockers, angiotensin converting enzyme inhibitors/angiotensin receptor blockers and nitrates was 93.3%, 97.3%, 94.1%, 76.3% / 14.1% and 41.2%. The treatment given to the patients was not completely in compliance with the ACC/ AHA guidelines (18.14%). Conclusion: The study provides an overall insight of the pattern of drugs prescribed to the patients with ACS which reveals the necessity of improving the rational prescribing of drugs in accordance with the standard guidelines.

Key words: Acute Coronary Syndrome, Prescription pattern, ACC/AHA guidelines, Rational drug use, Compliance.




 

The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmacy Practice (IJOPP) [ISSN-0974-8326] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 2008.

DOI HISTORY

IJOPP uses reference linking service using Digital Object Identifiers (DOI) by Crossref. Articles from the year 2014 are being assigned DOIs for its permanent URLs