Persistent Invasive Mole: A Case Report

Published on:January 2021
Indian Journal of Pharmacy Practice, 2021; 14(1):68-71
Case Report | doi:10.5530/ijopp.14.1.14


Persistent Invasive Mole: A Case Report


Authors and affiliation (s):

Prathyusha Kusuma1, Bhargavi Neela1, Balasankar Ramavath2,*

1Department of Clinical Pharmacy and Pharm.D, Vaagdevi College of Pharmacy, Hanamkonda, Warangal, Telangana, INDIA.

2Department of Oncology, Kakatiya Medical College, Mahatma Gandhi Memorial Hospital, Warangal, Telangana, INDIA.

Abstract:

Gestational trophoblastic disease is a group of interrelated lesions arising from the trophoblastic epithelium of placenta after abnormal fertilization. It is a disease of women with pregnancy related tumors. Invasive mole, a common manifestation of gestational trophoblastic disease is characterized by villi accompanying trophoblastic overgrowths and invasion which penetrate deep into the myometrium sometimes involving peritoneum or vaginal vault. Here we present a case of persistent invasive mole in a patient who underwent dilation and curettage twice with persistent vaginal bleeding and elevated serum β-human Chorionic Gonadotropin levels. Investigations revealed enlarged uterus with adnexal pathology, Histopathological examination of Dilation and Curettage showed presence of villi and trophoblastic tissue, increased serum β-hCG levels. The patient is successfully treated and managed with methotrexate chemotherapy. This study is focused on the significance of follow-up of the patient as there are more chances of recurrence associated with gestational trophoblastic disease.

Key words: Gestational trophoblastic disease, Invasive mole, β-hCG levels, Chemotherapy, Methotrexate.




 

The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
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Indian Journal of Pharmacy Practice (IJOPP) [ISSN-0974-8326] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 2008.

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