The Jarisch-Herxheimer reaction is defined as a transient immunological reaction, classically seen in patients during antimicrobial treatment of syphilis. Clinically, it manifests within 24 h with short-term constitutional symptoms (fever, chills, headache, myalgia) and exacerbation of existing cutaneous lesions. Herein, we present a case of Jarisch-Herxheimer reaction in an adolescent.
Key words: Jarisch-Herxheimer reaction, Syphilis, Adolescent, Immunological reaction, Antimicrobial treatment.