Etoricoxib Induced Toxic Epidermal Necrolysis: A Case Report

Published on: January 2024 

Indian Journal of Pharmacy Practice, 2024; 17(1):89-92 

Opinion | doi :10.5530/ijopp.17.1.15

Authors:

Saba Farooqui^1,*, Zuha Shyma¹ , Suha Zulekha¹, Jacintha Martis² , Adarsh V V¹

¹Department of Pharmacy Practice, Karavali College of Pharmacy, Vamanjoor, Mangalore, Karnataka, INDIA. 

²Department of Dermatology, Father Muller Medical College Hospital, Mangalore, Karnataka, INDIA.

Abstract:

Toxic Epidermal Necrolysis (TEN) is a rare and life-threatening skin reaction that can quickly lead to dehydration and infection. TEN is perhaps the most formidable disease encountered by dermatologists, and it remains as puzzling a disorder as it was when described by Lyell. Etoricoxib is a medication that has been associated with TEN. The ideal medical management of TEN should be multidisciplinary and requires early diagnosis and withdrawal of suspected/causative drug(s), supportive care, and specific therapy. Here we present a case of Toxic Epidermal Necrolysis due to Etoricoxib in an immune-compromised patient.

Key words:  Case Report, Etoricoxib, Toxic epidermal necrolysis