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Published on: January 2024 

Indian Journal of Pharmacy Practice, 2024; 17(1):83-86 

Opinion | doi:10.5530/ijopp.17.1.13 

Authors:

Pravin Kumar Ray*, Amit Kumar

 Department of Pharmacy Practice, Aditya College of Pharmacy, Surampalem, Andhra Pradesh, INDIA.

Abstract:

Orthostatic hypotension is a clinical condition characterized by a drop in blood pressure upon standing, leading to symptoms such as dizziness and lightheadedness. Benign Prostatic Hyperplasia (BPH) is a condition that affects many men and can cause Lower Urinary Tract Symptoms (LUTS). Some of the drugs used to treat BPH, such as alpha-blockers, can also cause OH. We present a case of a patient who experienced drug-induced orthostatic hypotension along with Vertigo. The management of drug-induced OH and vertigo included dose adjustment, drug discontinuation or switching, hydration, salt intake, compression stockings, physical countermeasures, and pharmacological interventions. In conclusion, drug-induced OH and vertigo are important adverse effects that should be considered in BPH patients who are treated with alpha-blockers or anti-muscarinics. Clinicians should be aware of the risk factors, diagnosis methods, and management strategies for these conditions. Further research is needed to compare the safety and efficacy of different drug classes and combinations for BPH patients with LUTS.

Key words:  Adverse effects, Dizziness, Drug-induced, Orthostatic hypotension, Vertigo