Neuropathic Pain and its Management

Anupam Kanti Bag¹, Shobha Rani R Hiremath^2,*

¹Department of Pharmacology, Aditya Bangalore Institute of Pharmacy Education and Research, Bangalore, Karnataka, INDIA.

²Department of Pharmacy Practice, Aditya Bangalore Institute of Pharmacy Education and Research, Bangalore, Karnataka, INDIA.

Abstract:

Pain is a distressing sensory and emotional experience connected to real or potential tissue damage, or one that is portrayed as such damage, according to the International Association for the Study of Pain (IASP).¹ There are many different pathophysiologic processes and interpretations of pain, which can vary greatly in severity, quality, and duration.² The process that follows an initial injury or illness of the somatosensory nerve system is known as neuropathic pain. Hyperalgesia, an abnormal heightened sensitivity to stimuli, and allodynia, a nociceptive reaction to non-noxious stimuli are characteristics of neuropathic pain. The aetiology or anatomic location of this illness, which is the outcome of numerous different pathogenic pathways, is typically used to define it.³ The conditions and pathophysiological states that predispose to the development of neuropathic pain include metabolic conditions like Peripheral Diabetic Neuropathy (PDN), neuropathies brought on by viral infections like post-herpetic neuralgia and HIV, leprosy, and leprosy, autoimmune conditions like multiple sclerosis and Guillain-Barre syndrome, chemotherapy-induced peripheral neuropathies, and damage to the nervous system caused by traumatic origin.⁴ Read more…