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Published on: November 2024
Indian Journal of Pharmacy Practice, 2024; 18(1):8-15.
Review Article| doi: 10.5530/ijopp.20250089

Authors and affiliation (s):

Satish Kumar Basattikoppalu Puttegowda, Mohith Shivaramu*, Balaji Skanda Manjunath, Rajesh Venkataraman,Ravindra Basaralu Nagarajappa

Department of Pharmacy Practice, Faculty of Pharmacy, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B. G. Nagara, Karnataka, INDIA.

ABSTRACT

This review article comprehensively explores the overview of artificial sweeteners and food colorants, examining their safety, regulatory status, and potential health effects. It explores the historical background of artificial sweeteners, covering key compounds like saccharin, aspartame and cyclamate, while also highlighting emerging alternatives such as rare sugars. The discussion extends to the physiological impacts of artificial sweeteners including their potential ill effects on blood glucose levels, obesity, gut microbiome, cardiovascular health, and cancer risk. Additionally, the review evaluates the safety and adverse effects of food colorants, emphasizing regulatory frameworks and potential health risks associated with synthetic food colorants like tartrazine and rhodamine B. It concludes by underlining the importance of cautious consumption, particularly among vulnerable populations like children and pregnant women, and advocates for ongoing research to inform evidence-based dietary guidelines and regulatory policies.

Keywords: Artificial Sweeteners, Food Colorants, Rare Sugar, Diabetes, Obesity, Cancer.