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Published on:October 2022

Indian Journal of Pharmacy Practice, 2022; 15(4):338-341

Case Report | doi:10.5530/ijopp.15.4.62

Authors:

Syed Zia Inamdar1,*, Sushilkumar Londhe1, Ravina Mehta1, Sumanyu Katageri1, Siddanagouda Biradar1, Shashidhar Devaramani2, Sharan Badiger2

1Department of Pharmacy Practice, BLDEAs SSM College of Pharmacy and Research Centre, Vijayapura, Karnataka, INDIA.

2Department of Medicine, Shri B M Patil Medical College Hospital and Research Centre, Vijayapura, Karnataka, INDIA.

Abstract:

Systemic sclerosis is a rare connective tissue disease categorized by extensive lung fibrosis, vascular and immunologic abnormalities. Autoimmune antibodies like anticentromere, anti-Scl-70 (anti-topoisomerase I), and anti-RNA polymerase II are commonly involved in progressive disease. Clinical presentations consist of Raynaud’s phenomenon, digital ulcers; pericardial effusion, and telangiectasia and are mostly associated with pulmonary complications like interstitial lung disease and pulmonary arterial hypertension. Disease-specific therapy is unavailable instead; symptomatic management is only the line of treatment. We report here a case of diffuse systemic sclerosis with interstitial lung disease and pulmonary arterial hypertension.

Keywords: Diffuse systemic sclerosis, Interstitial lung disease, Pulmonary arterial hypertension, Raynaud’s phenomenon.